https://www.lu-lab.org/publications daily 0.75 2026-02-24 https://www.lu-lab.org/contact daily 0.75 2022-07-05 https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1547762842964-BACNO0KJYTO5VC2YBN9X/image-asset.png Contact We are on the 5th floor of the UAB O’Neal Comprehensive Cancer Center. https://www.lu-lab.org/about-the-pi daily 0.75 2025-12-29 https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1547779201924-KQNYWUUFGQPOMY8MC9M3/Lu_Rui.jpg ABOUT THE PI https://www.lu-lab.org/research daily 0.75 2026-01-09 https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1547852179701-X1P01XNXWOXS1S6I3ZRJ/research_epigenetics.001.jpg RESEARCH Epigenetic modifications are another layer of control for interpreting the genetic sequences. https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1547853713269-V26GZX0QZPAU3JQJ5CS8/AML.001.jpeg RESEARCH We use AML as a model to study cancer epigenetics because of its unique characteristics. https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1547852844455-ULQIY3HR8BTS524UE4IB/tech.001.jpeg RESEARCH We use next-generation sequencing technology to profile epigenetic modifications at genome-wide levels. https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1548011138816-3IV5ROFWV30QJN3S26PC/newtargets.001.png RESEARCH We identify novel targets responsible for cancer-specific transcriptional and epigenetic regulations. https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/e02c3253-c5e8-4c4a-9d38-735487091b6d/research_drug_screen.png RESEARCH Chemical probes are not just drugs; they are invaluable tools that unlock the intricate secrets of biological mechanisms. https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1657044008176-PMPCWI5OYVGFSYX1HDFE/ACS.png RESEARCH https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1657044009142-TOM5TSX2NRDT36F0XS4D/ASH.png RESEARCH https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1657044010206-JTLDI461UCERSHHKPUAF/Concern.png RESEARCH https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1657044011275-Z9UH3IEE80395FEMNK1B/LRF.png RESEARCH https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1657044012689-U8GZQE2XK6WBWI48OFYS/Mark.png RESEARCH https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1721611668590-BM65DG859G2P90WS0PNT/GAFCR.png RESEARCH https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1657044013517-HGZESFBSIX8FKF5LRRHC/NCI.png RESEARCH https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1657044015127-1RPD72W90HYKTZG9VWUT/NIH.png RESEARCH https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1657044016371-RCBNG8MXR8DIQQFAUG3E/ONeal.png RESEARCH https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1657044017964-OP7UKHIAHVBO4E2FDUW5/UAB.png RESEARCH https://www.lu-lab.org/home daily 1.0 2024-07-22 https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1547910354987-606LZC0A0JQHLV09VO5J/UALBirmingham_header_11_4_16.jpg Home https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/b07968c2-cc3f-4f97-b86d-27da3c085efa/lu+lab+logo4.jpg Home https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1547934487873-TZ4CNR4HAAYJ64MEKI5V/wordcloud2.png Home https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1547921355424-YJGYZOY5ANEHAECZHPIT/lu%2Blab%2Blogo.001.jpg Home https://www.lu-lab.org/joinus daily 0.75 2022-07-05 https://www.lu-lab.org/buffers daily 0.75 2019-02-17 https://www.lu-lab.org/lab-members daily 0.75 2025-12-29 https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1568907033598-9U2NYEK7H1HI64PJB7UP/Lu.jpeg LAB MEMBERS Rui Lu Principal Investigator ruilu1 AT uabmc.edu https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/8f22bbd3-6b37-4d48-aed4-9558c2364f0d/pengcheng.jpg LAB MEMBERS Pengcheng Zhang Graduate Student, CANB pzhang AT uabmc.edu https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/45ae522e-224f-44bb-83d5-d1b3ac5216e3/xinyue.jpg LAB MEMBERS - Make it stand out Xinyue Zhou Graduate Student, GGB xinyuezhou AT uabmc.edu https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/a16fca96-3fb7-4c69-a780-84088282a238/DSC02811.jpg LAB MEMBERS Brittany Curtiss MSTP Student, GGB bmc2 AT uab.edu https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/ef9c9698-867f-4a8a-a9e4-4d6d4f777d20/IMG-3140.jpg LAB MEMBERS - Make it stand out Sajesan Aryal Graduate Student, GGB sajesan AT uab.edu https://www.lu-lab.org/news daily 0.75 2026-02-02 https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/5d2717e4-7c71-4037-9c76-c79f15851b4e/Pittmans_Scholars_2023_Photo.png NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/7f9060bf-f1de-4108-8810-d872b3363b28/3BLU_6zC_400x400.jpg NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/cd09d7a2-1bf6-4faa-9ea7-0730b2fc7954/American_Cancer_Society_Logo.svg.png NEWS - 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Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/a516bb47-bec0-4cc6-92d2-36dd77ea4c4c/WechatIMG10.jpg NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/aa682ca3-5aad-4c16-8c82-cbfe67f9fb46/FEBSJ.jpg NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1631288548778-J2G85CJ9HZZ1D26YJX2I/color-with-R-standard.png NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1628742452087-Q7VN5B60E8JZWPS8T9ZK/blood-advances-banner.png NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/0296b3ae-3357-4b91-ae3c-c976f593ba1c/American_Society_of_Hematology_logo.svg.png NEWS https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/60543713-ebb9-4f17-86f2-bf6e23241677/horizontal_logo.jpg NEWS https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/7387e4f9-3fb4-49df-9648-f1beb13b91fa/ETO3tJKXgAARJQu.jpg NEWS https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/13e24980-635d-4845-9a8f-c8b533d1664a/Cheaha-logo.jpg NEWS https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/cd09d7a2-1bf6-4faa-9ea7-0730b2fc7954/American_Cancer_Society_Logo.svg.png NEWS https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/1631288548778-J2G85CJ9HZZ1D26YJX2I/color-with-R-standard.png NEWS https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/62d505a6-55b7-4d0a-aff0-975eaf97571a/images.png NEWS https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/54bf23cc-09cb-4ef3-ab4e-d893d08e1d20/Unknown.jpg NEWS https://www.lu-lab.org/gallery daily 0.75 2025-12-29 https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/fc09755b-d677-4793-bb20-cd5c6a0fe747/F6924FE8-9380-4909-8C39-6E696E4F36D6_1_105_c.jpg GALLERY - Make it stand out Group at the ASH Annual Meeting, Atlanta (2021) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/f5e30df4-f5a9-41c7-a477-b1e17e2a1d8c/Screenshot_20221229_155606_Drive.jpg GALLERY Fish Market (2022) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/8f6e9ece-0a53-4bd9-b2f6-dd329654f880/IMG_0431.jpg GALLERY Cheaha State Park (2022) Photo credit: Lisa https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/0c3ba8e8-a8fd-4c10-bb5c-206c9f56db0b/IMG_8564.jpg GALLERY - Make it stand out Lisa’s Farewell Dinner at the Cheesecake Factory (2023) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/f2005bc1-b6c5-408c-a935-231ca3b2f22c/015E526D-0641-4B0A-B765-165352484A50_1_105_c.jpeg GALLERY - Make it stand out Xinyue Gives an Oral Presentation at the ASH Annual Meeting, San Diego (2023) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/2472eda0-6d42-497d-b597-ab3cb6076b03/IMG_9486.jpg GALLERY - Make it stand out The Great Pumpkin Patch, Hayden (2024) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/7b49202d-980d-4f76-a0bf-7a7bdc68b2c8/1000007863.jpg GALLERY - Make it stand out Celebrating Neha’s Graduation at El Barrio (2024) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/6ef7a2d4-c231-4b24-bf4b-b542fb084264/IMG_1308.jpg GALLERY Universal Studios, Orlando with the Mark groups (2025) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/b9a779b3-a874-4f71-b5f8-96e2bc3ef894/tempImageM4lOBo.jpg GALLERY - Make it stand out Sajesan Gives a Poster Presentation at the ASH Annual Meeting, Orlando (2025) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/ef4bbb0b-8c57-4076-9d18-7c512b67c983/6963D7F4-A186-421D-BD22-6684D82E13A9_1_105_c.jpeg GALLERY - Make it stand out Dinner at the ASH Annual Meeting, Atlanta (2021) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/76adb5ea-3af1-44a0-8e1f-1a4bb3674acc/IMG_6429.jpg GALLERY Cheaha State Park (2022) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/9dd85961-6b45-44f2-98dc-851edaa6edba/Screenshot_20221229_155606_Drive.jpg GALLERY - Make it stand out Winter Holiday Dinner at the Fish Market (2022) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/3f01f5f1-3af1-4eba-a736-4b11911aaad3/IMG_0615.jpg GALLERY - Make it stand out Sajesan, Pengcheng, and Rui at the Mark Group Retreat, Cookeville (2023) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/4875006a-35f4-4603-97d7-b229a312c2fe/02641162-79CD-4C1F-BCE3-5F63B5803393_1_105_c.jpeg GALLERY - Make it stand out Lu Lab at the ASH Annual Meeting, San Diego (2023) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/6a6eaa20-c159-4868-8db1-8f7ab235078f/20241006_135735%280%29.jpg GALLERY - Make it stand out The Great Pumpkin Patch, Hayden (2024) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/79a97e3a-0e2b-45b4-9e28-3200b5dd0c12/20241218_211748.jpg GALLERY - Make it stand out Winter Holiday Dinner at the Culinary Dropout (2024) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/0b8b054e-eb85-494e-ae2d-0cf961f703cf/IMG_0318.jpg GALLERY Universal Studios, Orlando (2025) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/2e34c227-ac62-4403-b08a-0f49cb6d2cbc/tempImageN0eMpB.jpg GALLERY - Make it stand out Pengcheng Gives an Oral Presentation at the ASH Annual Meeting, Orlando (2025) https://images.squarespace-cdn.com/content/v1/5c350523b98a78dd25ca9d6d/ce0a4738-1acd-4c84-a9bf-ccdde9bc1a25/MH2512063352-56.jpg GALLERY Pengcheng Receives the Outstanding Abstract Achievement Award at the ASH Annual Meeting, Orlando (2025)