1. R Lu, J Wang, Z Ren, J Yin, Y Wang, L Cai, GG Wang: A model system for studying the DNMT3A hotspot mutation (DNMT3AR882) demonstrates a causal relationship between its dominant-negative effect and leukemogenesis. Cancer Research 2019, 79(14): 3583-3594.

  2. Cai L, Tsai YH, Wang P, Wang J, Li D, Fan H, Zhao Y, Bareja R, Lu R, Wilson EM, Sboner A, Whang YE, Zheng D, Parker JS, Earp HS, Wang GG: ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer. Molecular Cell 2018, 72(2):341-354.

  3. Xu B, Cai L, Butler JM, Chen D, Lu X, Allison DF, Lu R, Rafii S, Parker JS, Zheng D, Wang GG: The Chromatin Remodeler BPTF Activates a Stemness Gene-Expression Program Essential for the Maintenance of Adult Hematopoietic Stem Cells. Stem Cell Reports 2018, 10(3):675-683.

  4. Zhang ZM*, Lu R*, Wang P, Yu Y, Liu S, Ji D, Gao L, Rothbart SB, Wang Y, Wang GG, Song J: Structural basis for DNMT3A-mediated de novo DNA methylation. Nature 2018, 554(7692):387-391. (*equal contribution)
    Highlighted in Cancer Discovery.

  5. Lu R, Wang GG: Pharmacologic Targeting of Chromatin Modulators as Therapeutics of Acute Myeloid Leukemia. Frontiers in Oncology 2017, 7:241.

  6. Lu R, Wang GG: Gene enhancer deregulation and epigenetic vulnerability. Oncoscience 2016, 3(11-12):299-301.

  7. Lu R, Wang P, Parton T, Zhou Y, Chrysovergis K, Rockowitz S, Chen W-Y, Abdel-Wahab O, Wade PA, Zheng D, Wang GG: Epigenetic Perturbations by Arg882-Mutated DNMT3A Potentiate Aberrant Stem Cell Gene-Expression Program and Acute Leukemia Development. Cancer Cell 2016, 30(1):92-107.
    Cover story; Highlighted in Cancer Cell and Cancer Discovery.

  8. Zhou Y, Wang L, Vaseghi HR, Liu Z, Lu R, Alimohamadi S, Yin C, Fu J-D, Wang GG, Liu J, Qian L: Bmi1 is a key epigenetic barrier to direct cardiac reprogramming. Cell Stem Cell 2016, 18(3):382-395.

  9. Yu H, He K, Wang L, Hu J, Gu J, Zhou C, Lu R, Jin Y: Stk40 represses adipogenesis through translational control of CCAAT/enhancer-binding proteins. Journal of Cell Science 2015, 128(15):2881-2890.

  10. Lu R, Wang GG: Tudor: a versatile family of histone methylation ‘readers’. Trends in Biochemical Sciences 2013, 38(11):546-555.

  11. Cai L*, Rothbart SB*, Lu R*, Xu B, Chen W-Y, Tripathy A, Rockowitz S, Zheng D, Patel DJ, Allis CD, Strahl BD, Song J, Wang GG: An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting. Molecular Cell 2013, 49(3):571-582. (*equal contribution)

  12. Yang A, Shi G, Zhou C, Lu R, Li H, Sun L, Jin Y: Nucleolin maintains embryonic stem cell self-renewal by suppression of p53 protein-dependent pathway. Journal of Biological Chemistry 2011, 286(50):43370-43382.

  13. Lu R, Yang A, Jin Y: Dual functions of T-box 3 (Tbx3) in the control of self-renewal and extraembryonic endoderm differentiation in mouse embryonic stem cells. Journal of Biological Chemistry 2011, 286(10):8425-8436.

  14. Li L, Sun L, Gao F, Jiang J, Yang Y, Li C, Gu J, Wei Z, Yang A, Lu R, Ma Y, Tang F, Kwon SW, Zhao Y, Li J, Jin Y: Stk40 links the pluripotency factor Oct4 to the Erk/MAPK pathway and controls extraembryonic endoderm differentiation. Proceedings of the National Academy of Sciences 2010, 107(4):1402-1407.

  15. Li H, Wang B, Yang A, Lu R,Wang W, Zhou Y, Shi G, Kwon SW, Zhao Y, Jin Y: Ly-1 Antibody Reactive Clone Is an Important Nucleolar Protein for Control of Self-renewal and Differentiation in Embryonic Stem Cells. Stem Cells 2009, 27(6):1244-1254.

  16. Wang BB, Lu R, Wang WC, Jin Y: Inducible and reversible suppression of Npm1 gene expression using stably integrated small interfering RNA vector in mouse embryonic stem cells. Biochemical and Biophysical Research Communications 2006, 347(4):1129-1137.